Lab Equipment Calibration and Validation

 
 

Comprehensive Lab Equipment Calibration

Our lab equipment calibration, validation, and repair services are critical to keeping your lab equipment and instruments operating at peak efficiency to avoid extended downtime that imperils your project schedule.

 
 

Available in Select Regions

Our factory trained and qualified engineers have an average of 20 years of experience to ensure we meet your equipment needs. We offer our services in San Diego, San Francisco, and Los Angeles as well as Arizona, Massachusetts, Nevada, and Utah.

 
 

Comprehensive Equipment Calibration

Our mission is to provide accurate, timely, documented calibrations that our customers can trust. We have a full-service ISO 17025 A2LA Accredited and ISO 9001:2015 AMS Certified calibration lab dedicated to providing premier instrument calibration services for a quality experience.

 
 

Service Flexibility

With mail-in, pickup, delivery, and on-site services available for all common lab equipment, you’ll be satisfied with your calibration experience, from the delivery and detail to the documentation you’ll receive at the end of the process.

 
 

Basing Your Calibration Provider Choice Solely on Price?

You Get What You Pay For

Calibration service providers operate and compete based on profit margin. The less time they spend calibrating an instrument, the less they need to charge, and the more competitive they appear to be on paper.

Fully accredited, Flagship Lab Services uses comprehensive procedures to specify uncertainty levels for calibration standards, determine pre-calibration steps to ensure proper equipment operation, and define the required calibration points used to verify your instrument’s full range of operation.

 
 

Equipment We Calibrate

All General Lab Equipment

With mail-in, pickup, delivery, and on-site services available for all common lab equipment, you’ll be satisfied with your calibration experience, from the delivery and detail to the documentation you’ll receive at the end of the process.

  • Freezers
  • Refrigerators
  • Liquid handlers
  • Spectrophotometers
  • Balances
  • Plate Readers
  • Autoclaves
  • Incubators
  • Centrifuges
  • HPLC
  • Thermal Cyclers (PCR)
  • Pressure Gauge
  • Torque Testers
  • and much more!
 
 

Weights Balance Scale Calibration

If you use a balance or scale for any of your measuring, you know how accurate and precise it must be for the desired results. Over time and with continuous use, the unit can become dirty and unreliable.

Our weights/balance/scale instrument calibration processes (which include our ISO 17025 A2LA Accreditation and ISO 9001:2015 AMS Certification) ensures that your equipment will be calibrated and science-ready.

 
 

Pressure Gauge Reading Inaccurately?

Even the highest quality gauges are subject to drift out of specification. If allowed, this can damage your results, and may be a risk to employee safety as well. Pressure gauge calibration is essential to precise results.

 
 

PCR Instruments

Since the light source changes over time, it’s recommended that halogen-based instrumentation be calibrated every six months, and LED-based be calibrated annually. The calibration procedure is identical to the manufacturer’s recommendations.

Real-Time PCR Instruments Covered:

  • Quant Studio 3
  • Quant Studio 5
  • Quant Studio 6
  • Quant Studio 7
  • Quant Studio 12K (non-OA)
  • 7300, 7500, 7500 Fast
  • Step One, Step One Plus
  • ViiA 7
 
 

Validation Services from Flagship Lab Services

Available in select areas, our validation services meet all your installation, operational, and performance qualification (IOPQ) needs.

San Diego is our immediate service area, but we also cover San Francisco and Los Angeles. Other locations we serve include Arizona, Massachusetts, Nevada, and Utah (zone travel charges will apply to remote locations).

 
 

Biological Safety Cabinets (BSCs)

We certify biological safety cabinets to meet NSF/ANSI 49 section Annex F Field Certification as well as the manufacturer’s specifications.

Primary Tests

  • Inflow velocity measurements
  • Downflow velocity measurements
  • HEPA filter integrity testing
  • Airflow visualization testing
  • Site installation testing and alarm calibration
  • Non-viable particle counting (optional)
  • Worker comfort and safety testing, including electrical safety, vibration, sound, & fluorescent/UV light (optional)
  • Decontaminate BSCs with vaporized hydrogen peroxide bioquell equipment.
 
 

Chemical Fume Hoods

DENS’ comprehensive ASHRAE 110 certification and face velocity testing of chemical fume hoods ensures this critical equipment is tested in accordance with AIHA/ANSI Z9.5, SEFA, ASHRAE 110, and OSHA.

ASHRAE 110 Testing

  • Inflow (face) velocity profiling
  • Airflow visualization testing
  • Cross draft airflow testing
  • Tracer gas containment test
  • Inflow (face) velocity profiling
  • Airflow visualization testing
  • Cross draft airflow testing
  • Tracer gas containment test
 
 

Cleanroom Testing

We test and certify cleanrooms to ISO 14644-1, ISO 144544-2, ISO 144644-3, and EU Annex 1 to ensure they are functioning to specific parameters and ISO classification.

Primary Tests

  • Airflow volume/velocity readings
  • Room air exchange rates
  • HEPA filter integrity testing
  • Non-viable particle counting
  • Temperature/relative humidity testing

Optional Tests

  • Air balancing
  • Airflow visualization testing/smoke testing
  • Lighting, vibration, & sound testing
  • Cleanroom recovery testing
 
 

HEPA/ULPA Filters Testing

We test HEPA filters to IEST-RP-CC006.3, IEST-RP-cco34.4, and ISO 146644.3 standards. HEPA filters can be tested as individual, unique devices as opposed to a portion of a larger cleanroom. HEPAs, which are a portion of other equipment such as glass washers, HEPA vacs, or process equipment, can also be tested. The main reasons for testing the filters are:

  • Qualification – installation testing
  • Leak testing
  • Health & safety requirements
 
 

Isolators

Isolators are used in general industry as well as compounding pharmacies. There are two types of isolators: positively pressurized aseptic isolators (CAI) and negative containment isolators (CACI). Both are primary engineering controls designed to meet the needs of USP Standards <797> and <800> for the compounding pharmacy.

Isolator Tests

  • HEPA filter integrity testing
  • Airflow velocity &/or volume
  • Chamber pressure testing
  • Work zone sterility testing
  • Product ingress/egress testing
  • Recovery time determination
  • Glove/sleeve breach testing
  • Interchange particle purge time determination
  • Particle containment integrity testing – CACI only
  • Volatile hazardous drug containment – CACI only
  • Interchange particle purge time determination – CACI only
 
 

Proper Planning Prevents...

Ensure the future of your processes and methods with our lab equipment validation services. Don’t wait for clinical trials to establish validation protocols or have your validations completed!

Our team not only develops your IOPQ protocols, but in most cases, we perform the IOPQ validation as well.

We offer IOPQ services for HPLCs, freezers, incubators (all types), environmental chambers, furnaces, water systems, balances, spectrophotometers, centrifuges, thermal cyclers, cryo-tanks, and many other pieces of lab equipment.

 
 

cGMP Requirements for Your...

We can help you determine these requirements for your:

  • Facility (sanitation, design, and construction)
  • Equipment (mechanical, electronic, environmental)
  • Production and process
  • Holding and distribution
  • Consumer complaints
  • Record keeping
 
 

Lab Calibration FAQ's

In the context of lab research, it typically means adjusting or standardizing your equipment so it can be more precise. This can include marking the graduations on a measuring device, or figuring out how much an instrument deviates from standard and adjusting for that difference.

Calibration is the procedure of comparing a reference with a known error margin against a device (for example a pressure gauge) under test. If the device doesn’t match the reference, then we adjust it to match, or at least come close, the desired measuring accuracy. The reference measurement instrument must be more accurate than the pressure gauge to be calibrated, and it must also be traceable. To calibrate a pressure gauge, we will need to check the values throughout the entire measuring range, zero point, intermediate values, and the full-scale value.

Calibration is a comparison between a known measurement (the standard) and the measurement using your instrument.

It is important to calibrate equipment to help assure accurate measurements and production of quality products with reduced errors and recalls. It is also important to calibrate equipment to foster innovation and the development of new technologies, as accurate measurements are foundational to both.